PhD defence : Ms. Léa Pinon : today !

Léa defended her PhD thesis today in front of an hybrid jury (Y. Carrasco, F. Leal-Calderon and A. Asnacios in remote, F. Brochard, J. Husson in person).

During these last 3.5 years, Léa worked under the shared supervision of Paolo (P. Pierobon, U932, Institut Curie) and myself, with a PhD scholarship from the IPV program (Sorbonne Université).

CNRS 80|PRIME 2020 granted !

Our collaborative and interdisciplinary project aiming at deciphering phagocytosis mechanisms, involving the group of Florence Niedergang (Biology of Phagocytes, Institut Cochin), the group of Jean-Maurice Mallet and Blaise Dumat (Laboratoire des Biomolécules, Département de Chimie, ENS) and our team.

After a long selection process, we have selected Ms. Laura Jacquelin, pharmacist and student of the Biomedical Engineering Master, for a PhD on the project. She will start around September, after validation of her application by the graduate school.

LIME from home !

Despite the confinement, our team was able to start some projects, and host (in remote) several students :

  • Sarah Duclos-Ivetitch (M1, Materials Science and Engineering Master) for an internship focused on the simulation of centrifugal sorting.
  • Romane Vinot (L3, ENS Paris Saclay) for a bibliographical study (and some home experiments :-)) on the control of capillary flows in porous media.

Some news

Some news from the team, since last fall 2018. I’ll start from the most recent :

  • I’ve been hosted for 2 weeks (’twas 10 days at the beginning, but a strike from SAS company allowed me to stay a little bit longer) at the Department of Clinical Microbiology of Umeå University (Sweden), in the group of Ass. Pr. M. Bally, thanks to a funding from the TOR program from the Institut Français de Suède. Lots of discussions, visits, experiments, and we hope a long lasting collaboration.
  • Lorraine has left the lab last month, and started a new postdoc at the Laboratoire Jean Perrin (Sorbonne Université). Her results in our team are starting to be published. Still under review, but the preprint is online.
  • Lucie Lacour (M1, Chemistry, Sorbonne Université) joined the team for a 3 months internship.
  • Kaori’s work on the development of microfluidic setups to study plant development is now online, and under review for publication. The preprint is online though, if you want to give a look.
  • Lea’s work on a new, more efficient protocol to functionnalize emulsion droplets has been accepted in Langmuir. This work started during her master’s internship here, and was finished during the first months of her PhD.
  • A first paper related to our collaborative work with A. Utada and N. Obana (U. Tsukuba) has been published in Microbes and Environnement. It describes the existence of a distinct subpopulation in the WT Alcanivorax Borkumensis.
Tavelsjö lake, Västerbotten, Sweden (End of April 2019)

Alexandra (Sasha) defended her PhD thesis

Mentored by Yong Chen and Jean-François Berret (U. Diderot), Sasha has spent almost 2 years at IPGG with us, working on the reconstitution of lung alveoli on chip. A lot of biology, engineering and microfluidics involved !

Sasha will be sailing around the world for a couple of weeks/months, but you can read her profile here.

Congrats to Dr. Matton and Dr. Mesdjian !

This end of semester was quite heavy, with two PhD graduations !
Pascal, who worked on the synthesis of fluorescent glycolipids to functionalize droplets graduated last week. He did his PhD with two advisors, J.M. Mallet and me.
Olivier, who worked on the developement of a microfluidic chip to perform statistical studies of B-cell antigen extraction, graduated yesterday.

Congratulations to both of them ! It is a good start for their career.

Engineer/Postdoc and M2 positions available

We are currently recruiting for projects taking place at IPGG :

  1. an engineer or postdoc to work on an applied interdisciplinary project to develop a new method to purify cells and organelles using homemade functionalized microparticles.
    The project involves the Institut Curie (Pablo Vargas, for immunology and cell biology) and the Pôle Microfluidique of the ENS Chemistry department (Jacques Fattaccioli, for chemistry and particle formulation).
    This position is offered, initially, on a fixed-term contract of 12 months. Extension could be considered based on the project advancement and future funding.
    The candidate should hold a M.Sc., engineering degree or PhD in biology, biophysics,  or related fields, have a strong interest in applied research and have a good expertise in cell manipulation. Background on surface functionalization, colloidal particles formulation, etc. will be a plus.
    Interested candidates should send a cover letter explaining their relevant work experience, a curriculum vitae and contact details of two references by e-mail to Jacques Fattaccioli ( and Pablo Vargas (
  2. a M2 intern, within the context of a collaboration between our team and the IJPB plant biology lab (INRA AgroParistech).
    We aim at studying the possibility to replace current processes based on mechanical cell lysis and centrifugation to perform plant cell fractionation and organelles (e.g. lipid droplets) separation using a specifically designed microfluidics chip.
    Regarding the techniques, the proposal is intended for student wishing to work in an interdisciplinary environment and acquire knowledge in microfabrication, plant cell manipulation and biology, microscopy, etc. The project is suitable for physicists with an interest for biology.
    Interested candidates should send a cover letter explaining their relevant work experience, a curriculum vitae and contact details of two references by e-mail to Jacques Fattaccioli (

Some news from the first semester…


News were scarce lately, and it is now time to summarize what happened during this last months (in fact … almost a year!) :

  • September 2016 : Lorraine joined the team  to work on the study of phagocytosis of functionnalized emulsion droplets.
  • November 2016 : Alexandra, who works for her PhD with Yong and Sandrine on an organ-on-a-chip project, started to spend some time at IPGG.
  • January 2017 : Kaori joined to work on a joint project with collaborators from IJPB-INRA AgroParisTech. Stay tuned for news to come 🙂
  • February 2017 : Léa started her M2 internship, and say what ? She will stay from 3 more years since she was selected for a UPMC IPV PhD scholarship. Her subject will be related to B cells, droplets and microfluidics.
  • June 2017 : I graduated for my Habilitation à Diriger des Recherches. Enfin ! From now on I can officially mentor PhD students, from the administrative point of view.
  • August 2017 : I’m currently hosted for 2 weeks at the Nomura lab (Tsukuba University, Japan) since our PRC Sakura grant to work together with my friend and collaborator Andy Utada was accepted. The grant will cover exchanges between his team and ours for 2017-2018 period.

OK, soon, summer vacations will start. And then la rentrée !

A bientôt.

N.B. Picture credits : U. Queensland, Australia